Hypermorphic botulism was a disease, a mutated form of botulismWP that was extant in the 23rd century.
History and specifics
In an alternate timeline version of the year 2270, Georges Mordreaux poisoned several people with hypermorphic botulism, including Judge Desmoulins, Jenniver Aristeides, Ian Braithewaite, and his lawyer, Lee. (TOS novel: The Entropy Effect)